Big Mouth

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Andrew Rannells

Leander / Matthew MacDell (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Joe Wengert

Caleb / Lump Humpman (voice)

Ayo Edebiri

Missy Foreman-Greenwald / Mosaic Missy (voice)

June Diane Raphael

Richard Kind

Paula Pell

Neil Casey

Detective Dumont / Lars (voice)

Jessica Chaffin

Shannon Glaser / Grace / Intellect Sphinx (voice)

Jon Daly

Jak Knight

DeVon / Gina's Brother #2 (voice)

Chelsea Peretti

Diaphragm (voice)

Seth Morris

(voice)

👤

Mark Rivers

(voice)

Gil Ozeri

Jew Fishman (voice)

Nathan Fillion

Nathan Fillion (voice)

Kat Dennings

Leah Birch / Lorraine the Hormone Monstress (voice)

Gina Rodriguez

Gina Alvarez / Gina Parrot (voice)

David Thewlis

Lionel St. Swithens (voice)

Thandiwe Newton

Heather Lawless

Jenna Bilzerian (voice)

Maria Bamford

Brandon Kyle Goodman

Walter (voice)

Mark Duplass

Whitmer Thomas

Camden (voice)

Paul Scheer

Kurt Bilzerian (voice)

Ali Wong

Zachary Quinto

Aiden (voice)

Stephanie Beatriz

👤

Emily Altman

Milk (voice)

Chloe Fineman

Leah Birch (voice)

Rob Huebel

Mr. Lizer (voice)

Natasha Lyonne

Suzette (voice)

Gary Cole

Matthew's Father (voice)

Jean Smart

Jack McBrayer

Jack (voice)

John Gemberling

Security Guard / Bus Driver's Son (voice)

Craig Robinson

Harvey Brooks (voice)

Michaela Watkins

Cantor Dina Reznick (voice)

Fran Gillespie

(voice)

Kristen Bell

Uninterested Girl (voice)

👤

Ashley London

The Virgin Mary / Waitress (voice)

Zach Woods

Sock (voice)