Big Mouth

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Andrew Rannells

Matthew (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Joe Wengert

Steven Tyler Glade Plug-In / Zombie (voice)

Ayo Edebiri

Missy Foreman-Greenwald / Mosaic Missy (voice)

June Diane Raphael

Richard Kind

Marty Glouberman (voice)

Jessica Chaffin

Paula Pell

Barbara Glouberman / Lola's Couch Pillow (voice)

Neil Casey

Lars (voice)

Jon Daly

Judd Birch (voice)

Jak Knight

DeVon (voice)

Chelsea Peretti

Diaphragm (voice)

Seth Morris

(voice)

👤

Mark Rivers

Michael Stipe Tampon (voice)

Gil Ozeri

Wiggles (voice)

Nathan Fillion

Nathan Fillion (voice)

Kat Dennings

Leah Birch / Lorraine the Hormone Monstress (voice)

Gina Rodriguez

Gina Alvarez (voice)

David Thewlis

Shame Wizard (voice)

Thandiwe Newton

Maria Bamford

Heather Lawless

Jenna Bilzerian (voice)

Brandon Kyle Goodman

Walter the Lovebug (voice)

Mark Duplass

Whitmer Thomas

Paul Scheer

Kurt Bilzerian (voice)

Ali Wong

Ali (voice)

Zachary Quinto

Aiden (voice)

Stephanie Beatriz

👤

Emily Altman

Olivia / Filmstrip Narrator (voice)

Chloe Fineman

Rob Huebel

Mr. Lizer (voice)

Natasha Lyonne

Suzette (voice)

Gary Cole

Andrew's Father (voice)

Jean Smart

Jack McBrayer

Jack (voice)

John Gemberling

Tyler the Hormone Monster (voice)

Craig Robinson

Craig (voice)

Michaela Watkins

Cantor Dina Reznick (voice)

Fran Gillespie

Maddie the American Girl Doll / Choir Girl (voice)

Kristen Bell

Uninterested Girl (voice)

👤

Ashley London

Skank (voice)

Zach Woods

Daniel (voice)